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Neoplasms (C00-D49)

ICD 10 CM Chapter C00-D49 of the ICD-10-CM contains the codes for most benign and all malignant neoplasms. Certain benign neoplasms, such as prostatic adenomas, may be found in the specific body system chapters. To properly code a neoplasm it is necessary to determine from the record if the neoplasm is benign, in-situ, malignant, or of uncertain histologic behavior. If malignant, any secondary (metastatic) sites should also be determined.

  • Notes:
    • Functional activity
    • All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
    • Morphology [Histolog

  • C00-C14 Malignant neoplasms of lip, oral cavity and pharynx (C00-C14)
  • C15-C26 Malignant neoplasms of digestive organs (C15-C26)
  • C30-C39 Malignant neoplasms of respiratory and intrathoracic organs (C30-C39)
  • C40-C41 Malignant neoplasms of bone and articular cartilage (C40-C41)
  • C43-C44 Melanoma and other malignant neoplasms of skin (C43-C44)
  • C45-C49 Malignant neoplasms of mesothelial and soft tissue (C45-C49)
  • C50 Malignant neoplasms of breast (C50)
  • C51-C58 Malignant neoplasms of female genital organs (C51-C58)
  • C60-C63 Malignant neoplasms of male genital organs (C60-C63)
  • C64-C68 Malignant neoplasms of urinary tract (C64-C68)
  • C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system (C69-C72)
  • C73-C75 Malignant neoplasms of thyroid and other endocrine glands (C73-C75)
  • C7A Malignant neuroendocrine tumors (C7A)
  • C7B Secondary neuroendocrine tumors (C7B)
  • C76-C80 Malignant neoplasms of ill-defined, other secondary and unspecified sites (C76-C80)
  • C81-C96 Malignant neoplasms of lymphoid, hematopoietic and related tissue (C81-C96)
  • D00-D09 In situ neoplasms (D00-D09)
  • D10-D36 Benign neoplasms, except benign neuroendocrine tumors (D10-D36)
  • D3A Benign neuroendocrine tumors (D3A)
  • D37-D48 Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes (D37-D48)
  • D49 Neoplasms of unspecified behavior (D49)

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